Solutions by Therapeutic Area

Therapeutic Area-Specific Compliance Solutions

Every therapeutic area has unique compliance requirements—from fast-track designations in oncology to compassionate use in rare diseases. tfives provides therapeutic area-specific compliance solutions that address the unique challenges of your drug development program. Built for your therapeutic area. Optimized for your compliance needs.

Built for Your Therapeutic Area

Each therapeutic area has unique regulatory pathways, safety monitoring requirements, and compliance considerations. tfives provides specialized solutions tailored to your therapeutic area's specific needs.

🎗️

Oncology

Fast-Track Designations. Complex Protocols. High AE Burden. We've Got You Covered.

Oncology trials are complex—fast-track designations, breakthrough therapy designations, complex protocols with multiple arms, high adverse event burden, survival endpoints, and compassionate use programs. Compliance must be perfect, but timelines are aggressive. tfives provides oncology-specific compliance solutions that accelerate development while maintaining regulatory excellence.

Your Oncology Compliance Platform:

  • ComplianceIQ: AI model validation for oncology drug discovery—48-hour assessments for target identification models
  • Clinical Bundle: Protocol compliance monitoring, safety signal detection, Grade 3-4 toxicity tracking
  • AskRexi: Fast-track designation guidance, breakthrough therapy requirements, FDA oncology guidance
  • Pharmacovigilance: Automated AE detection, dose modification tracking, safety database management

Perfect for: Oncology drug development programs requiring fast-track designations, complex protocols, and aggressive timelines

🔬

Rare Disease & Orphan Drugs

Small Populations. Natural History Studies. Compassionate Use. Registry Trials. We Understand.

Rare disease development is unique—small patient populations, natural history studies, compassionate use programs, expanded access, patient registries, and ultra-orphan drug designations. Compliance must support patient advocacy involvement while maintaining regulatory rigor. tfives provides rare disease-specific compliance solutions that enable patient-centric development while ensuring regulatory excellence.

Your Rare Disease Compliance Platform:

  • Clinical Bundle: N-of-1 trial management, patient registry compliance, natural history study data integrity
  • AskRexi: Orphan drug designation guidance, expanded access requirements, compassionate use regulations
  • DataGovernanceIQ: Patient data privacy for small populations, HIPAA compliance for registries
  • ComplianceIQ: AI model validation for rare disease drug discovery—small dataset compliance

Perfect for: Rare disease and orphan drug development programs requiring patient-centric approaches and specialized regulatory pathways

🧠

Neurology & CNS

Cognitive Endpoints. Long-Term Follow-Up. Specialized Assessments. Caregiver Consent. We Support It All.

Neurological drug development requires specialized compliance—cognitive endpoints (ADAS-Cog, MoCA), long-term follow-up studies, caregiver consent, specialized assessments, and rare disease overlap. Compliance must support complex patient populations while maintaining data integrity. tfives provides neurology-specific compliance solutions that enable specialized assessments while ensuring regulatory compliance.

Your Neurology Compliance Platform:

  • Clinical Bundle: Cognitive assessment compliance, caregiver consent management, long-term follow-up tracking
  • DataGovernanceIQ: Patient data privacy for cognitive assessments, HIPAA compliance for caregiver data
  • ComplianceIQ: AI model validation for neurological drug discovery—specialized endpoint compliance
  • AskRexi: FDA neurology guidance, cognitive endpoint requirements, caregiver consent regulations

Perfect for: Neurological and CNS drug development programs requiring specialized assessments and long-term follow-up

❤️

Cardiology & Cardiovascular

Long-Term Trials. MACE Adjudication. DSMB Requirements. Cardiac Imaging QC. We Ensure Compliance.

Cardiovascular drug development requires specialized compliance—long-term trials, MACE (Major Adverse Cardiac Events) adjudication, DSMB (Data Safety Monitoring Board) requirements, cardiac imaging quality control, and Holter monitoring. Compliance must support complex cardiovascular endpoints while maintaining data integrity. tfives provides cardiology-specific compliance solutions that enable cardiovascular endpoint compliance while ensuring regulatory excellence.

Your Cardiology Compliance Platform:

  • Clinical Bundle: MACE adjudication compliance, DSMB reporting, cardiac imaging quality control
  • DataGovernanceIQ: Cardiac imaging data integrity, Holter monitoring data privacy
  • Pharmacovigilance: Cardiovascular AE detection, MACE event tracking, safety signal detection
  • AskRexi: FDA cardiology guidance, MACE endpoint requirements, DSMB regulations

Perfect for: Cardiovascular drug development programs requiring MACE adjudication, DSMB oversight, and long-term trial management

💉

Vaccines & Infectious Disease

Healthy Volunteers. Challenge Studies. Pandemic Trials. EUA. Immunogenicity. We Enable Rapid Development.

Vaccine development requires specialized compliance—healthy volunteer studies, challenge studies, pandemic trial requirements, Emergency Use Authorization (EUA), mass vaccination trials, and immunogenicity assays. Compliance must support rapid development while maintaining regulatory rigor. tfives provides vaccine-specific compliance solutions that enable rapid vaccine development while ensuring regulatory excellence.

Your Vaccine Compliance Platform:

  • Clinical Bundle: Challenge study compliance, immunogenicity assay data integrity, mass vaccination trial management
  • AskRexi: EUA requirements, FDA vaccine guidance, pandemic trial regulations
  • DataGovernanceIQ: Immunogenicity data integrity, healthy volunteer data privacy
  • Manufacturing Bundle: Vaccine manufacturing GMP compliance, batch record management

Perfect for: Vaccine and infectious disease development programs requiring rapid development, EUA pathways, and immunogenicity compliance

⚕️

Metabolic & Endocrinology

Chronic Disease Management. Lifestyle Interventions. Continuous Monitoring. Long-Term Safety. We Support It All.

Metabolic and endocrinology drug development requires specialized compliance—chronic disease management, lifestyle interventions, continuous glucose monitoring, dietary compliance, and long-term safety monitoring. Compliance must support real-world data collection while maintaining regulatory rigor. tfives provides metabolic-specific compliance solutions that enable chronic disease management while ensuring regulatory compliance.

Your Metabolic Compliance Platform:

  • Clinical Bundle: Continuous monitoring compliance, dietary recall data integrity, HbA1c endpoint tracking
  • DataGovernanceIQ: Continuous glucose monitoring data privacy, lifestyle intervention data integrity
  • CommercialCore: Patient engagement for chronic disease management, adherence tracking
  • AskRexi: FDA diabetes guidance, metabolic endpoint requirements, chronic disease regulations

Perfect for: Metabolic and endocrinology drug development programs requiring chronic disease management and real-world data collection

One Platform. Every Therapeutic Area. Complete Compliance.

tfives provides therapeutic area-specific compliance solutions across all major therapeutic areas. Whether you're developing oncology drugs, rare disease therapies, neurological treatments, cardiovascular medications, vaccines, or metabolic interventions—tfives has the compliance solutions you need.

Therapeutic Area Coverage

Oncology
Rare Disease
Neurology & CNS
Cardiology
Vaccines
Metabolic
Psychiatry
Pediatrics
And More

Ready to Find Your Therapeutic Area Solution?

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